Oha. Der Merz ist ein Depp und taugt nicht als Kanzler oder als Politiker, aber das kann böses verheisen.

Unfortunately, I do remember some people misbehaving in such a manner. It weren’t any official statements, but there were undertones accusing them of laziness.

To produce ABs in cell culture you usually create a hybridoma cell line, by fusing the B-Cell to an immortal tumour cell line (as you postulated). This approach does however require you to identify the cells that produce the proper antibody.

It gets much easier if you know the exact sequence/structure. To learn this (or find a better one) it is also possible to generate libraries of antibody sequences with semi-random hypervariable regions (the part that binds the antibody) using for example phages that will display any protein on their surface area and then measuring the binding affinity! This is called - drum roll - phage display (very creative).

Alright, enough trivia for now.

Ich besuche gerade Ulm! Wirklich eine wunderschöne Altstadt, verspielt und romantisch, und die Aussicht vom Münster ist top.

Poking straight at the hornets’ nest, I see.

I know a town with I think five or six large furniture (or general household item) stores basically next to each other. Big brands.

It is probably a combination of factors: The area is easy to reach by car, it’s easy to supply by truck, plenty of space for storage and people actively come there to shop furniture - yes you will be competing with five different stores, but since the customer base travels quite a bit anyway, you’d be stupid to set up shop in a different town. People will walk/drive 5 minutes to check a different store if they already came all this way, but they probably won’t head to a store two towns over just to compare prices.

Looks pretty good! Aaaand I’m hungry now

Well, if you say “no homo” at any point it’s not … unless you want it to be ;)

There’s this game called “Scissors, scissors, scissors”. It" s like “Rock, paper, scissors” , but you can only do scissors and when two people do the same move they have to make out.

I agree. Human rights and dignity are not negotiable. Not for mass murderers, rapists, Nazis, or Jeff Bezos. Not for anyone. Disagree, oppose, undermine, fight, but do not ever dehumanise.

I mean, the plot of Ghost in the Shell sounds pretty close from what I recall: Poor people can only afford cheap bionics, but cannot repair or replace them once support ends.

Heiße Filmeinstellung

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I know that I am misunderstanding the headline, but I just imagined Trump ordering companies to pump the oil back into the ground because earth didn’t pay any tariffs or alleviate any trade deficits.

es helfen nur Mollis

Ja gut, ne. Finde ich nicht in Ordnung, solche Aufrufe. Wo wir schon beim Thema sind, wie wäre es mal mit Gras anfassen?

Poles aren’t men? EDIT: Or Fins?

A) Evolution is not directed. If a pre-tiger happens to be a more advantageous colour, it will have more offspring. There is no goal.

B) An orange tiger has the same camouflage from its prey’s point of view as a green one, which is the thing that really matters. There is only one species a tiger is afraid of, and it’s humans. I would wager that the orange also happens to act as a signal colour, both to other tigers and other predators (such as humans). Less run-ins and less territorial dispute sound pretty good.

Did her cooking change over time? What is/used to be her favourite meal?

Not specifically directed at OP, but I am sick of those truncated graphs.

Also, fuck Trump. Not in a goof way.

Ufzs, das sind zu großen Teilen keine Selbsties. Aber ja, was ein Lappen.