I use Android Tiers, Glittertech (no surgery), and Rimatomics. My colonies always end up with just the most insane defenses with super powered androids.
Anyone who makes their way to my colony will find the most lavish place on the rim.
*We may or may not be using human hearts to till our soil.
I do install way too many mods and break my game with all sorts of error, first of all. Then (with constant errors of course) i love to do something with 5 or so people but i always end with too many leather and fur, dunno what to do with them most of time.