Results: In the fully adjusted model, significant positive associations between P_CARB and CVD risk were observed in the pooled analysis, showing that the HRs (95% CIs) for CVD across increasing quartiles of P_CARB were 1.00 (reference), 1.16 (0.94-1.44), 1.25 (0.96-1.63), and 1.48 (1.08-2.03). The restricted cubic spline regression analysis confirmed a linear dose-response relationship between P_CARB and CVD risk in both cohort studies, with all p-values for nonlinearity >0.05.

Conclusion: Our findings suggest that a carbohydrate-based diet high in proportion to total energy intake may increase the risk of CVD among middle-aged Korean adults, underscoring the importance of balanced macronutrient distribution. However, more research is needed to evaluate the sources and quality of carbohydrates in relation to CVD risk in this population.

Full Paper: https://doi.org/10.1016/j.clnu.2023.06.013

  • jet@hackertalks.comOPM
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    5 days ago

    Fructose metabolizing like ethanol and causing liver dysfunction is still pretty controversial in the mainstream nutrition community, right?

    I’ve seen no controversy here, the metabolic pathway is the same, its mechanical and observable. There are people saying whole fruits are a net-benefit in-spite of this. But I haven’t seen any serious advocate pushing for high fructose corn syrup as a health food.

    I have violent acute symptoms when I imbibe, which… is kinda good thing to some extent. I’ve got a feedback mechanism

    It’s nice to have feedback!