• Mohamed@lemmy.ca
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    2 个月前

    It is true, it seems, that Nicotine treats ADHD. There is at least one study that showed nicotine patches (18h and 24h ones) provide a mild to moderate relief for ADHD in people that do not use nicotine otherwise (e.g. nonsmokers). So, it doesn’t just treat the symptoms of nicotine withdrawal.

    Cigarette smoke is known to contain a clinically significant amount of MAO inhibiters that are not nicotine. MAO inhibiters are regularly used to treat depression and anxiety, and theoretically could treat ADHD since MAOI’s generally prevent breakdown of dopamine. There is some nuance here.*

    • For example, there are different types of MAO (monoamine oxidase - an enzyme that breaks down monoamines. Dopamine is an example of a monoamine), like MAO-A vs MAO-B, which break down different monoamines, and MAOI’s (MAO Inhibitors) differ on whether they inhibit A, B or both. Furthermore, there are reversible vs irreversible MAOI.
    • theblips@lemm.ee
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      2 个月前

      This is super interesting. Can you link the sources? I’d be interested in knowing if this MAO deal is exclusive to cigarettes or is also present in the ecologically superior and marginally healthier pipe tobacco

    • Bizzle@lemmy.world
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      2 个月前

      Going to tell my wife she’s ableist for giving me a hard time about the cigarettes, this is the best day of my life. Thank you

    • HEXN3T@lemmy.blahaj.zone
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      2 个月前

      I also understand that nicotine is a cholinergic. Cholinergic compounds play an important role in memory, attention, and motivation, as well as some critical muscular function. Nicotine is actually beneficial in this regard, aside from its negatives.

    • prole@lemmy.blahaj.zone
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      2 个月前

      Nicotine is also supposedly helpful for schizophrenia in some way… Might be the same thing (MAO related)