I’d say that working within the limits of the medium, in this case the gameboy camera, means that you need to understand the limits, and understand them well. What are the max resolution, focal length, and contrast ratio that you can get?

Once you have that figured out you can start planning your shots and pick an environment that works within those limits. Once you can take a picture that isn’t washed out etc, at that point it’s just the normal elements of composition, rule of thirds, light-source etc. Since the camera is monochrome, you may be able to do something interesting with light vs shadows, but I suspect that contrast will need to be super high for it to work.

Finally if you are actually serious about this, you will very quickly reach the limits of the equipment meaning that you’ll ultimately be unsatisfied with the outcome even after putting a lot of planning work into it. There is a reason people suggest using pinhole cameras as a first foray into photography. The pinhole camera is much more capable then the Gameboy while still having a lot of limitations that encourage experimentation.