Personally, I think Questionable Content, Kevin and Kell, and Dumbing of Age are great for this. They all have a ton of history, and Kevin and Kell is actually one of the longest running webcomics ever.
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XKCD Has got to be up there.
I would recommend Kill 6 Billion Demons, Bouletcorp (though it’s English site has been very wonky to me recently, the French site works fine), Gunnerkrigg Court, Devil’s Candy and Unsounded.
They are all long-runners with beast archives to match. Specially Gunnerkrigg Court, it has been going strong since 2005 with 89 chapters (around 20 to 30 pages each though it varies) and counting.